(S)-1-(4-chloro-3-fluorophenyl)ethanaMine hydrochloride - Names and Identifiers
(S)-1-(4-chloro-3-fluorophenyl)ethanaMine hydrochloride - Physico-chemical Properties
Molecular Formula | C8H9ClFN
|
Molar Mass | 173.62 |
Density | 1.215 |
Boling Point | 226.7±25.0 °C(Predicted) |
pKa | 8.50±0.10(Predicted) |
Storage Condition | 2-8°C(protect from light) |
(S)-1-(4-chloro-3-fluorophenyl)ethanaMine hydrochloride - Introduction
(R)-1-(4-chloro-3-fluorophenyl) ethanamine (also known as (R)-3-chloro-4-fluorophenethylamine) is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Molecular formula: C8H8ClFN
-Molecular weight: 175.61g/mol
-Appearance: colorless or yellowish liquid
-Melting point:-17 ℃
-Boiling point: 172-173 ℃
-Density: 1.269g/cm³(20 ℃)
-Refractive index: 1.531 (20 ℃)
-Optical rotation:[α]D25 = 117.7 ° (c = 1, methanol)
Use:
(R)-1-(4-chloro-3-fluorophenyl) ethylamine is a chiral pharmaceutical intermediate that can be used to synthesize biologically active compounds. It is often used as a chemical reagent in organic synthesis, medicine, pesticide and other fields.
Preparation Method:
The preparation method of (R)-1-(4-chloro-3-fluorophenyl) ethylamine can be carried out by the following steps:
1. the chloro-trifluorobenzene and ethylamine are placed in an organic solvent to react.
2. Using a suitable chiral carrier, a gold-gilling hydrogenation reaction is carried out through a reaction of a chiral ligand catalyst to obtain the target compound.
Safety Information:
(R)-1-(4-chloro-3-fluorophenyl) ethylamine is generally safe under correct use and storage, but some safety precautions still need to be paid attention:
-This compound is irritating, avoid contact with skin, eyes and mucous membranes.
-Follow appropriate laboratory safety procedures, such as wearing protective glasses, gloves and protective clothing.
-Avoid directly inhaling its vapor or dust, and operate in a well-ventilated place.
-When storing, keep it in a dry, cool place to avoid contact with oxidants or high temperature areas.
-In case of discomfort or misuse, seek medical attention immediately and bring information about the compound.
Last Update:2024-04-09 19:05:44